High Alert Drugs

Prescription Error Overdose Leads to Paralysis, Victim Hopeful for Recovery

May 19, 2011 | Lebowitz & Mzhen

Our Maryland pharmacy misfill injury attorneys have been following the recent developments in the tragic Walmart prescription error incident from 2008 that caused a teenager to suffer a pain medication overdose that led to paralysis.

When Jessie Scott was 18, and suffering from strep throat pain, his doctor prescribed a low-dose of the pain reliever, oxycodone hydrochloride. After receiving the prescription from Walmart, Jessie’s mother administered one dose to her son.

In a grave prescription drug error, the Walmart pharmacist reportedly failed to dilute the drug, and the prescribed dosage of 5 milligrams was actually around 100 milligrams, causing a prescription drug overdose. Jessie went into a coma, suffered organ failure and paralysis.

Scott, who is now 20 years old, has reportedly experienced some remarkable changes physically and psychologically, making incredible strides since the horrific incident that caused his disabilities. Thanks to a court prescription error lawsuit settlement with Walmart, Jessie’s parents were able to build an area in their house with special accommodations that allow him to be transported from room to room. He can now raise his arms, hold his head upright, wiggle his toes, and even kick. Although the odds seem to be against him, Jessie holds out hope that he will walk again.

FDA Redesigns Pharmacy Packet Inserts to Avoid Medication Error Injury

May 9, 2011 | Lebowitz & Mzhen

According to a recent article in the Wall Street Journal, a new national initiative is underway to make prescription medications clearer, and to decrease the rise of medication error that lead to hospitalizations and emergency room visits from patients who take their medication incorrectly—which according to the National Community Pharmacists Association happens to three out of every four Americans.

The U.S. Food and Drug Administration (FDA) is reportedly planning to test a new one-page information sheet to replace the many leaflet inserts and medication guides that are widely used in retail pharmacy chains across the country. And the U.S. Pharmacopeial Convention, the organization responsible for setting quality standards that are enforced by the FDA for the strength, purity and quality of medicines, has also developed a new program to create national standards for prescription labels, which currently vary greatly from pharmacy to pharmacy. The national label standard would require clearer instructions on the medication dosage, the medication timing and clearly state the purpose of the medication—to reduce medication and pharmacy error injury.

Currently, in pharmacies across the country, consumers may receive three different forms of drug information and pamphlets with their prescription medication—drug package inserts that are written by the drug manufacturer with FDA approval, drug guides for specific classes of drugs and products that are required by the FDA, and third-party consumer medical information. And according to the WSJ, recent FDA studies have shown that the drug information offered to consumers does not provide reliable understanding with the people taking the drugs, and is often conflicting in instruction, or even inaccurate, which could lead to patient harm or injury.

According to a recent FDA risk-communication advisory panel, more than half of adults misread or misunderstand one or more of common drug prescription precautions or warnings. In one study, patients were found to better understand language on warning labels that was simple and specific, like “use only on your skin” as opposed to “for external use only.” For consumers with lower English literacy skills, picture icons were provided, like a sun with a black bar, with the phrase, “limit your time in the sun.”

Pharmaceutical Company Must Reveal Fentanyl Patch Data in Wrongful Death Lawsuit

April 27, 2011 | Lebowitz & Mzhen

In a recent Maryland pharmacy error injury lawyer blog, our attorneys discussed the increasing medication errors resulting from the incorrect administration of Fentanyl, the strong pain relieving medication patch. If a medication error occurs with Fentanyl, the improper administration of the drug can lead to a drug overdose or even wrongful death.

In a recent wrongful death lawsuit that our Baltimore pharmacy error attorneys have been following, Monika Standing and Chris Bristol are suing Watson Pharmaceuticals and two corporate affiliates after their daughter Nicole died three weeks after using the 75-microgram time-released fentanyl patches in January 2008. Nicole’s parents claim that her fentanyl patch, made by Watson, leaked—causing Nicole to suffer an overdose of the fentanyl gel inside, leading to her death.

According to the lawsuit, the fentanyl patches made by Watson used a faulty design, creating a patch that was prone to leaks, which lead to possible overdoses and deaths. Other patches made by competitors reportedly had a safer patch design that did not leak.

Last week, as the case developed, a Los Angeles County Superior Court Judge reportedly ordered Watson Pharmaceuticals to turn over pain patch samples, any materials used for commercials or marketing, all written communication between Watson Pharmaceuticals and the U.S. Food and Drug Administration involving the usage and safety of the fentanyl patch, all experiments or studies done involving fentanyl patch levels in the user’s bloodstream when using the patch, all autopsy reports and papers involving deaths while using the patch, and transcripts of all depositions taken of any Watson employee or key expert witness in a previous defective fentanyl pain patch lawsuit, and also ordered certain key executives from the company to testify about the pain patches.

Children’s Hospitals Form Collective Effort on Patient Safety to Prevent Medication Errors

April 13, 2011 | Lebowitz & Mzhen

According to a recent article in Pharmacy Practice News that our Washington D.C. pharmacy error injury attorneys have been following, a group of children’s hospitals in Ohio have prevented around 3,600 adverse drug events and surgical site infections, along with saving over $5 million, during an 18-month program initiative that was launched in 2009.

The initiative, called “Solutions for Patient Safety,” was reportedly launched with support of the Cardinal Health Foundation, who gave 1.5 million, along with the shared motivation of children’s hospitals in an effort to work together to eliminate preventable injury or harm to children.

Before the initiative began, each children’s hospital in the state reportedly collected data on adverse drug events in a different way—making it very difficult to compare or share information within hospitals. After conducting audits of a random collection of charts, the group was able to come together and manually identify and review the root cause of adverse events, and pinpoint a set of common concerns.

The initiative found that the main collective medication error problem was constipation from opioids, as well as over sedation as a result of the narcotics. Although constipation is not a life-threatening adverse drug event, it can reportedly add to more time in the hospital, more lab work, and tests, which can all add to additional costs.

500 Unapproved Prescription Cough and Cold Medications Banned by FDA

March 22, 2011 | Lebowitz & Mzhen

Our Maryland-based prescription drug error attorneys have been following the U.S. Food and Drug Administration’s recent announcement, ordering the makers of around 500 prescription cold, cough and allergy medications to take the drugs off the pharmacy shelves, as they have not been proven to be safe and effective.

According to the FDA, the prescription drugs in question have not been linked to any major problems or drug-related injuries, but the FDA is still concerned that the medical problems associated with the drugs could be seriously under reported.

The agency claims that the drugs have not been evaluated by the FDA, and taking them may be more of a risk to the consumer than taking over-the-counter (OTC) medications to treat the same symptoms, that have been approved. The FDA also claimed that the action is necessary to protect consumers from any health and safety risks posed by these unapproved drugs, as the agency does not know how they are made, whether they are effective, or what is in them.

One of the problems that the agency found was with time-release drugs, which are reportedly hard to manufacture, and can release too slowly or not at all if quality controls in the manufacturing of the drug are inadequate. The FDA also made a move against unapproved products that contain drug combinations that could be considered dangerous, like combining two antihistamines, which could react in oversedation.

Hospital Sued for Wrongful Death After Patient Dies from Drug Error

March 22, 2011 | Lebowitz & Mzhen

Our Baltimore-based pharmacy error injury attorneys have been following the recent and tragic news story surrounding a Massachusetts woman, who endured a hospital medication error during a routine hospital stay that reportedly led to her wrongful death.

According to the Boston Globe, Geraldine Oswald was hospitalized in November of last year to clear up an infection that had developed after breaking her shoulder. While staying in the hospital, she reportedly received too much Lepirudin, a blood-thinning drug used to prevent the formation of potentially dangerous blood clots. The medication overdose affected Oswald’s own blood clotting ability, leading to internal bleeding. While in the hospital’s care, Oswald reportedly hemorrhaged for 12 hours before her wrongful death—which the hospital later stated could have been preventable.

The family of Oswald recently stated that they plan to file a wrongful death lawsuit against Massachusetts General Hospital, two nurses and five doctors, claiming that Oswald was supposed to be treated for a common infection, and instead received a blood thinner that was 30 times too high in dosage, and proved to be lethal.

According to the hospital’s report, the on-duty nurse understood the dosage intended for Oswald, but made a medication error while administrating the dose into the I.V. pump. In a meeting with Oswald’s family members after her death, the hospital reportedly stated that the medical error was preventable.

Dangerous Safeway Pharmacy Mix-up Gives Pregnant Woman Wrong Medication

February 5, 2011 | Lebowitz & Mzhen

In recent news that our pharmacy misfill injury attorneys in Washington, D.C. have been following, a medication error occurred in a local pharmacy, after a pregnant woman in Colorado was mistakenly given the incorrect medication for another patient who had a similar sounding name.

According to KDVR-TV, Mareena Silva, who is six weeks pregnant, went to Safeway to pick up her antibiotics and was mistakenly given the prescription for Maria Silva, containing Methotrexate, a medication reportedly used to treat cancer.

By the time Silva realized the pharmacy misfill, she had already reportedly taken the first pill. Silva reportedly rushed back to Safeway, where the pharmacist recommended that she throw the pill up, as it had been 30 minutes since she took the medication. Her doctor then sent an ambulance to Safeway.

Methotrexate, the drug Silva took due to the prescription mix-up, can reportedly cause birth defects in an unborn baby. The drug is also reportedly used to cause abortions in pregnancies that are troubled. The manufacturer also warns that there have been reported deaths linked to the incorrect administration of this drug.

After picking up what she thought was the antibiotic, the pharmacist reportedly even stated that the prescribed drug was not good for a pregnant woman. What Silva didn’t realize at the time is that the pharmacist was talking about the Methotrexate.

Study Finds Small Doses of Drugs From Syringes Could Cause Medication Error in Children

February 4, 2011 | Lebowitz & Mzhen

As our Baltimore County pharmacy error attorneys discussed in a recent blog, according to a recent study by the Agency for Healthcare Research and Quality (AHRQ), medical errors are a leading cause of personal injury and death in this country, and rates for possible adverse drug events were three times higher with children than adults in hospitals, with an even higher rate for infants in intensive care units.

In a new study, published in the Canadian Medical Association Journal, a report found that preparing small medication dosages from syringes for infants and children can be dangerously inaccurate and cause medication dosing errors.

According to the report, in administering potent drugs to young patients, small doses are often prepared from medication stock of less than 0.1 milliliter (mL) in size, but the current equipment used to administer the drug does not allow for the correct and accurate measuring of drug volumes that are less than 0.1 mL.

Dr. Christopher Parshuram, the author of the study, who works in the University of Toronto’s Department of Pediatrics and directs the University of Toronto Center for Patient Safety’s Pediatric Patient Safety Research, stated that medications regularly requiring small doses include narcotics and sedatives that are extremely powerful, such as morphine and fentanyl—both drugs that as our Maryland medication error attorneys have reported in a recent blog, have a high-risk for medication mistakes which could lead to patient injury or wrongful death.

FDA Reports on Fatal Morphine Oral Solution Medication Errors

January 26, 2011 | Lebowitz & Mzhen

According to a recent report from the U.S. Food and Drug Administration (FDA) that our Washington D.C. medication error lawyers have been following, a morphine solution that was approved by the administration last year, has been linked to a series of morphine overdoses and deaths due to medication error—leading federal regulators to issue a warning and initiate a label change to prevent personal injury or death.

The FDA’s recent notification to the health care industry and consumers reported on the overdoses and deaths that have occurred as a result of morphine sulfate oral solution medication errors, most of which are linked to the high potency (100 mg per 5mL) product, where solutions ordered in milligrams (mg) were erroneously mistaken for milliliters (mL) of the drug, causing fatal overdoses.

When milligrams (mg) are misread and confused for milliliters (mL), the patient dosage could reportedly be as high as 20 times stronger than the dosage intended for the patient, which could result in a drug overdose. Other medication mistakes were reportedly caused by confusion in medication dosage, and understanding the morphine concentration in the oral solution.

As our medication mistake attorneys in Baltimore, Maryland have reported in a related blog, according to the Institute of Medicine’s (IOM), 1.5 million people are injured by preventable medication errors every year, with 98,000 annual deaths from medical errors—7,000 of which are due to medication mistakes.

The morphine sulfate oral solution is manufactured by Roxane Laboratories, Inc., and is used to tread moderate to severe chronic and acute pain with patients who are opioid-tolerant. In a blog from this week, our attorneys discussed the danger associated with an incorrect administration of a powerful prescription pain medication and the prevalence of fatal medication overdoses with patients who are opioid-intolerant and are erroneously prescribed these medications.

ISMP—Prescribing Fentanyl Pain Medication for Short-Term Pain Be Deadly

January 25, 2011 | Lebowitz & Mzhen

In a recent blog, our Baltimore County pharmacy misfill attorneys discussed the prevalence of medication error cases resulting from the incorrect administration of the strong pain relieving medication Fentanyl, also called Duragesic—that if used erroneously can lead to a drug overdose and even wrongful death.

According to a recent article by Michael Cohen, president of the Institute for Safe Medication Practices, (ISMP), Fentanyl is around 100 times more powerful than morphine and for that reason should only be prescribed to people with chronic and long-term pain, like cancer patients, who are opiod-tolerant from already taking heavy prescription narcotics, or opioids, for one week or longer. As Cohen describes, Fentanyl is effective for three days, keeping patients with long-term pain from having to medicate repeatedly during the day.

As our Baltimore, Maryland medication error attorneys reported in a related blog, Fentanyl should only be used with patients who are opioid-tolerant because even the lowest strength Fentanyl patches have the ability to cause major side effects, like breathing difficulties, which can lead to wrongful death. According to the 2007 FDA warning, the Fentanyl patch should not be used with patients who are not opioid-tolerant.

Cohen explains that patients who are opioid tolerant and tolerant of other prescription pain medications have less of a chance of experiencing breathing difficulty when using a Fentanyl patch that is properly prescribed, as stopped breathing is often what kills patients in an overdose. According to Cohen, the big medication mistake currently being made by doctors is using Fentanyl to treat pain post-surgery pain, called acute postoperative pain, which should be treated by using other painkillers.

The ISMP has reportedly been receiving fatality reports since the drug has been introduced, but September of last year proved to be a devastating month for Fentanyl medication overdoses, as three tragic deaths occurred after patients were given Fentanyl by their doctors erroneously, with doses that were too high, at 50mcg/hour.