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Federal investigators and prosecutors in Indiana believe that four doctors at various medical center locations may be responsible for having caused as many as 27 deaths.

The individuals who died were all patients at a group of clinics in the area. Two of the doctors accused of causing the deaths are also the co-owners of the locations. The charges include various drug and conspiracy charges. A federal Drug Enforcement Agency investigation filed some 95 felony charges against nine employees, which included the two doctor owners.

According to an affidavit, the clinic was known as a go to place for individuals seeking access to prescription medications. According to some individuals, it was sometimes referred to as “the candy shop.”

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An Alabama jury recently awarded a widow $850,000 after her husband was allegedly administered triple the normal dosage of medication for a pre-existing condition, and died as a result on Christmas Day.

The jury reportedly spent hours deliberating before delivering the verdict against the man’s doctor, for having purportedly caused the 62 year old’s death. The man was initially hospitalized for pneumonia, and had spent 11 days there for treatment. According to reports, he was given three times the amount of lithium that he actually needed in order to treat his bipolar disorder.

The man’s wife has already made a $1 million settlement with the hospital where the man was undergoing treatment at the time of the accidental overdose. The man had apparently been transferred to a different hospital for treatment, where blood tests showed elevated lithium levels, and he was then moved to another location for dialysis where he died.

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The family of a young girl recently filed a $750,000 federal lawsuit against her local pharmacy, alleging that the business wrote the incorrect directions on her prescription for a seizure medication, causing the girl to take five times the proper dosage of the drug.

According to the lawsuit, the little girl was given a prescription when she was four years old for two milliliters of an anti-seizure medication, to be taken twice a day. However, when the prescription was filled, the instructions stated that the girl should be given two teaspoonfuls twice a day. One teaspoon is the equivalent of almost five milliliters. The pharmacist in the case stated that she repeated the dosage back to the doctor at the time it was filled, and it was confirmed as written.

The young girl’s mother stated that immediately after giving her daughter the incorrect dosage, the girl suffered a serious seizure requiring immediate hospitalization and treatment at a local hospital. According to the lawsuit, the girl became catatonic, and the girl was later transferred to a Children’s Hospital where she remained unconscious for some time. Once she regained consciousness, the girl was unable to walk, and had to be fed baby food, resulting in a 17-18 pound weight loss. She reportedly still suffers side effects from the incorrect drug dosage, and is afraid of taking medicine.

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A doctor/medication safety specialist recently wrote an article about a common abbreviation that could lead to severely adverse consequences in patients. The article, which appears in the web version of the Pharmacy Times, discusses one common abbreviation for acetaminophen, APAP, which is based upon the chemical composition of the drug, that could lead to a deadly overdose when patients take other medications not knowing that they contain the same drug.

For example, in one case following surgery, a 56 year old man was prescribed a hydrocodone/acetaminophen combination drug, but on the label it was abbreviated Hydrocodone/APAP. The instructions said to, “take one tablet by mouth every 4 to 6 hours as needed for pain.” The patient took the medication as instructed, but had insufficient pain relief, so he began taking additional over the counter acetaminophen, and followed those instructions, taking two caplets every 4 to 6 hours as needed.

Following some four days of this combination, the patient returned to the doctor for his post-op appointment, he complained of a lack of appetite, nausea, vomiting, and abdominal pain. The doctor was able to determine that the man was taking over 8 g of acetaminophen per day. The patient told the doctor that the pharmacist did not counsel him on the daily limit of acetaminophen, and that he was unaware that his prescription also contained acetaminophen. The patient was subsequently admitted to the hospital and treated for acute hepatotoxicity, and he luckily made a full recovery.

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In probably one of the most egregious incidents that have occurred in pharmacy error news lately, a young woman was intentionally given the incorrect prescription medication in order to induce a miscarriage.

The 27 year old Florida woman was apparently deceived by her boyfriend who colluded with a local pharmacy employee, and she is now suing the pharmacy that provided the medication.

According to the woman’s lawsuit, she reportedly thought that she was receiving amoxicillin, which had allegedly been prescribed by her boyfriend’s father, an obstetrician who’d confirmed her pregnancy. Instead, however, she was given misoprostol, a stomach ulcer medicine that can cause abortion and birth defects. According to her recently filed negligence lawsuit, just a few days later, the woman had a miscarriage.

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As previously discussed on this blog, one of the most common errors made by prescribing doctors, or in those who input values, is accidentally increasing the dosage, such as in the entering of “10.0 mg,” when the person should have input “1.0 mg.” Even though the error is only a matter of a decimal, it could kill or severely injure a patient.

Medication errors such as these occur frequently, at an estimated one million incidents each year, contributing to 7,000 deaths.

According to recent research, the best known way for hospitals to protect patients from errors is by adopting technology called computerized physician order entry (CPOE). The way these systems work, is that when the person who is entering the prescription into the system enters the values, they are checked against the patient’s records, allergies, etc. This information is then cross referenced for safety and other measures before being sent to the pharmacy. In the opening hypothetical, a properly performing system would alert the physician to the misplaced decimal in the order. Some of the best systems may have actually prevented the order from being written in the first place.

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A woman who was given a prescription for medication to help ease her anxiety before a dental appointment now has good reason to be skeptical of pharmacies.

The woman was given a prescription by her dentist to take prior to a dental appointment for 0.25 milligrams of Triazolam. When she picked up her medication from a local pharmacy, she assumed that the instructions on the label were accurate, and after paying for the medicine, was not consulted by a pharmacist. The label instructed the woman to take four pills an hour before treatment.

The woman reports losing memory just after her dental appointment began. She does not recall a friend driving her home or the rest of the evening. She credits her boyfriend having stayed over for the relatively uneventful rest of the day. The woman’s friend said she had seemed “completely normal,” which concerned the woman to think what could have happened under the circumstances. According to pharmacy experts, amnesia is a well known side effect of an overdose of the drug Triazolam. Other serious side effects include cardiac arrest, coma and seizures.

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Johnson & Johnson recently made the decision to make some changes in the way it labels Tylenol, specifically in regards to adding additional warnings of the potential dangers the drug may pose.

The warning will make it explicitly clear that the over-the-counter drug contains acetaminophen, a pain-relieving ingredient that’s the nation’s leading cause of sudden liver failure.

These preventative measures are believed to be related to the fact that the company is reportedly currently facing more than 85 personal injury lawsuits in federal court blaming Tylenol for various liver injuries and deaths.

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A Harford County jury recently awarded nearly $1 million to the estate and surviving family members of a woman who allegedly received excessive pain medication following a leg ulcer surgery.

According to reports regarding the case, the plaintiffs alleged that the doctors at the Harford County Hospital administered morphine, oxycodone, and other narcotics to the woman under the mistaken belief that they had received permission to provide palliative care to the woman, rather than attempting to strive for the woman’s full recovery. The hospital reportedly denies the allegations of negligence, and plans to appeal the judgment.

While only very limited factual information was reported regarding this case, it seems that the family is alleging that the hospital administered a form of unauthorized palliative care, which resulted in the death of the patient. Palliative care is distinct from assisted suicide, and as such is protected by U.S. Supreme Court case law. Essentially, it occurs when caregivers can no longer perform additional or helpful medical procedures to improve the patient’s prognosis, so they instead focus on alleviating the pain as best as they can. Oftentimes, these high levels of pain medications can lead to death.

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Individuals in Ireland with diabetes may be at a serious risk of injecting themselves with dangerously high levels of insulin, due to an error in glucose monitoring kits recently discovered.

According to the authorities, some 4,100 boxes of test strips, which are directly used to measure glucose levels in the blood of diabetics, are being recalled due to a manufacturing error which could give a false reading. The strips were part of a faulty batch of GlucoMen LX Sensor test strips.

The strips, which are used as home kits, may result in an overestimation of the diabetic’s blood glucose level, which could potentially result in them injecting themselves with too much insulin.

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